Pattern of Antimicrobial Resistance to <i>Escherichia Coli</i> Among the Urinary Tract Infection Patients in Bangladesh

Goutam Kumar Acherjya; Keya Tarafder; Rina Ghose; Din Ul Islam; Mohammad Ali; Nazma Akhtar; Rajashish Chakrabortty; Satya Ranjan Sutradhar

doi:doi:10.11648/j.ajim.20180605.17

Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh

Goutam Kumar Acherjya, Keya Tarafder, Rina Ghose, Din Ul Islam, Mohammad Ali, Nazma Akhtar, Rajashish Chakrabortty, Satya Ranjan Sutradhar

Published in American Journal of Internal Medicine (Volume 6, Issue 5)

Received: 21 July 2018 Accepted: 14 August 2018 Published: 10 October 2018

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Abstract

Urinary Tract Infection (UTI) is very common in our day-to-day clinical practice. Among all the organisms Escherichia coli (E coli) is the most common but antimicrobial resistance becomes an alarming issue for UTI management now a days. Aim of this study is to assess the pattern of antimicrobial resistance to E coli among the UTI patients in Jashore, Bangladesh. This observational study was conducted from February, 2017 to January, 2018 in the district of Jashore, Bangladesh. We recruited 696 patients of both sex with UTI only infected by E coli. We had excluded the patients with UTI caused by other than E coli, female during menstruation, pregnancy, history of taking antibiotics within last 21 days, catheterization within 1 month and pelvic organ & genito urinary tract surgery within 6 months. Evaluation of antimicrobial resistance was done according to the standard bacteriological methods. Mean age of our study cases was 41.46±17.21 years with the range from 15 to 91 years. More than 85% participants were female with a sex ratio was 8:1.5. Reproductive age group ranged from 21 to 50 years was affected most commonly which constituted approximately two-third of our study. Our study revealed that the maximum antimicrobial resistance to E coli was Cotrimoxazole (95.0%), followed by Ceftazidime (75.7%), Gentamicin (70.3%), Amikacin (69.0%), Imipenam (58.9 %,), Cefixime (58.0%), Ciprofloxacin (57.3%), Azithromycin (56.0%), Cefuroxime (46.6%), Cefotaxime (37.4%), Ceftriaxone (35.2%), Meropenem (32.2%), Nitrofurantion (4.7%). With the high magnitude of antimicrobial resistance to E coli among the UTI patients even with extended generation of Cephalosporins, Carbapenams, Ciprofloxacin, Cotrimoxazole, Azithromycin and Aminoglycosides, our recommendation as first line empirical treatment option in UTI should be Nitrofurantoin due to low resistance pattern.

Published in	American Journal of Internal Medicine (Volume 6, Issue 5)
DOI	10.11648/j.ajim.20180605.17
Page(s)	132-137
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2018. Published by Science Publishing Group

Keywords

UTI, E coli, Antibiotic Resistance, Antibiotic Susceptibility

References

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APA Style

Goutam Kumar Acherjya, Keya Tarafder, Rina Ghose, Din Ul Islam, Mohammad Ali, et al. (2018). Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh. American Journal of Internal Medicine, 6(5), 132-137. https://doi.org/10.11648/j.ajim.20180605.17

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ACS Style

Goutam Kumar Acherjya; Keya Tarafder; Rina Ghose; Din Ul Islam; Mohammad Ali, et al. Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh. Am. J. Intern. Med. 2018, 6(5), 132-137. doi: 10.11648/j.ajim.20180605.17

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AMA Style

Goutam Kumar Acherjya, Keya Tarafder, Rina Ghose, Din Ul Islam, Mohammad Ali, et al. Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh. Am J Intern Med. 2018;6(5):132-137. doi: 10.11648/j.ajim.20180605.17

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@article{10.11648/j.ajim.20180605.17,
  author = {Goutam Kumar Acherjya and Keya Tarafder and Rina Ghose and Din Ul Islam and Mohammad Ali and Nazma Akhtar and Rajashish Chakrabortty and Satya Ranjan Sutradhar},
  title = {Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh},
  journal = {American Journal of Internal Medicine},
  volume = {6},
  number = {5},
  pages = {132-137},
  doi = {10.11648/j.ajim.20180605.17},
  url = {https://doi.org/10.11648/j.ajim.20180605.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20180605.17},
  abstract = {Urinary Tract Infection (UTI) is very common in our day-to-day clinical practice. Among all the organisms Escherichia coli (E coli) is the most common but antimicrobial resistance becomes an alarming issue for UTI management now a days. Aim of this study is to assess the pattern of antimicrobial resistance to E coli among the UTI patients in Jashore, Bangladesh. This observational study was conducted from February, 2017 to January, 2018 in the district of Jashore, Bangladesh. We recruited 696 patients of both sex with UTI only infected by E coli. We had excluded the patients with UTI caused by other than E coli, female during menstruation, pregnancy, history of taking antibiotics within last 21 days, catheterization within 1 month and pelvic organ & genito urinary tract surgery within 6 months. Evaluation of antimicrobial resistance was done according to the standard bacteriological methods. Mean age of our study cases was 41.46±17.21 years with the range from 15 to 91 years. More than 85% participants were female with a sex ratio was 8:1.5. Reproductive age group ranged from 21 to 50 years was affected most commonly which constituted approximately two-third of our study. Our study revealed that the maximum antimicrobial resistance to E coli was Cotrimoxazole (95.0%), followed by Ceftazidime (75.7%), Gentamicin (70.3%), Amikacin (69.0%), Imipenam (58.9 %,), Cefixime (58.0%), Ciprofloxacin (57.3%), Azithromycin (56.0%), Cefuroxime (46.6%), Cefotaxime (37.4%), Ceftriaxone (35.2%), Meropenem (32.2%), Nitrofurantion (4.7%). With the high magnitude of antimicrobial resistance to E coli among the UTI patients even with extended generation of Cephalosporins, Carbapenams, Ciprofloxacin, Cotrimoxazole, Azithromycin and Aminoglycosides, our recommendation as first line empirical treatment option in UTI should be Nitrofurantoin due to low resistance pattern.},
 year = {2018}
}

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TY  - JOUR
T1  - Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh
AU  - Goutam Kumar Acherjya
AU  - Keya Tarafder
AU  - Rina Ghose
AU  - Din Ul Islam
AU  - Mohammad Ali
AU  - Nazma Akhtar
AU  - Rajashish Chakrabortty
AU  - Satya Ranjan Sutradhar
Y1  - 2018/10/10
PY  - 2018
N1  - https://doi.org/10.11648/j.ajim.20180605.17
DO  - 10.11648/j.ajim.20180605.17
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 132
EP  - 137
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20180605.17
AB  - Urinary Tract Infection (UTI) is very common in our day-to-day clinical practice. Among all the organisms Escherichia coli (E coli) is the most common but antimicrobial resistance becomes an alarming issue for UTI management now a days. Aim of this study is to assess the pattern of antimicrobial resistance to E coli among the UTI patients in Jashore, Bangladesh. This observational study was conducted from February, 2017 to January, 2018 in the district of Jashore, Bangladesh. We recruited 696 patients of both sex with UTI only infected by E coli. We had excluded the patients with UTI caused by other than E coli, female during menstruation, pregnancy, history of taking antibiotics within last 21 days, catheterization within 1 month and pelvic organ & genito urinary tract surgery within 6 months. Evaluation of antimicrobial resistance was done according to the standard bacteriological methods. Mean age of our study cases was 41.46±17.21 years with the range from 15 to 91 years. More than 85% participants were female with a sex ratio was 8:1.5. Reproductive age group ranged from 21 to 50 years was affected most commonly which constituted approximately two-third of our study. Our study revealed that the maximum antimicrobial resistance to E coli was Cotrimoxazole (95.0%), followed by Ceftazidime (75.7%), Gentamicin (70.3%), Amikacin (69.0%), Imipenam (58.9 %,), Cefixime (58.0%), Ciprofloxacin (57.3%), Azithromycin (56.0%), Cefuroxime (46.6%), Cefotaxime (37.4%), Ceftriaxone (35.2%), Meropenem (32.2%), Nitrofurantion (4.7%). With the high magnitude of antimicrobial resistance to E coli among the UTI patients even with extended generation of Cephalosporins, Carbapenams, Ciprofloxacin, Cotrimoxazole, Azithromycin and Aminoglycosides, our recommendation as first line empirical treatment option in UTI should be Nitrofurantoin due to low resistance pattern.
VL  - 6
IS  - 5
ER  -

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Author Information

Goutam Kumar Acherjya

Upazila Health Complex, Bagherpara, Jashore, Bangladesh
Keya Tarafder

Department of Microbiology, Jashore Medical College & Hospital, Jashore, Bangladesh
Rina Ghose

Department of Gynaecology and Obstretics, Jashore Medical College & Hospital, Jashore, Bangladesh
Din Ul Islam

Department of Microbiology, Jashore Medical College & Hospital, Jashore, Bangladesh
Mohammad Ali

Department of Hematology, National Institute of Cancer Research and Hospital, Dhaka, Bangladesh
Nazma Akhtar

Emergency Department, National Institute of Cardiovascular Disease, Dhaka, Bangladesh
Rajashish Chakrabortty

Department of Medicine, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh
Satya Ranjan Sutradhar

Department of Medicine, Mymensingh Medical College & Hospital, Mymensingh, Bangladesh

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APA Style

Goutam Kumar Acherjya, Keya Tarafder, Rina Ghose, Din Ul Islam, Mohammad Ali, et al. (2018). Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh. American Journal of Internal Medicine, 6(5), 132-137. https://doi.org/10.11648/j.ajim.20180605.17

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ACS Style

Goutam Kumar Acherjya; Keya Tarafder; Rina Ghose; Din Ul Islam; Mohammad Ali, et al. Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh. Am. J. Intern. Med. 2018, 6(5), 132-137. doi: 10.11648/j.ajim.20180605.17

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AMA Style

Goutam Kumar Acherjya, Keya Tarafder, Rina Ghose, Din Ul Islam, Mohammad Ali, et al. Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh. Am J Intern Med. 2018;6(5):132-137. doi: 10.11648/j.ajim.20180605.17

Copy | Download

@article{10.11648/j.ajim.20180605.17,
  author = {Goutam Kumar Acherjya and Keya Tarafder and Rina Ghose and Din Ul Islam and Mohammad Ali and Nazma Akhtar and Rajashish Chakrabortty and Satya Ranjan Sutradhar},
  title = {Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh},
  journal = {American Journal of Internal Medicine},
  volume = {6},
  number = {5},
  pages = {132-137},
  doi = {10.11648/j.ajim.20180605.17},
  url = {https://doi.org/10.11648/j.ajim.20180605.17},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20180605.17},
  abstract = {Urinary Tract Infection (UTI) is very common in our day-to-day clinical practice. Among all the organisms Escherichia coli (E coli) is the most common but antimicrobial resistance becomes an alarming issue for UTI management now a days. Aim of this study is to assess the pattern of antimicrobial resistance to E coli among the UTI patients in Jashore, Bangladesh. This observational study was conducted from February, 2017 to January, 2018 in the district of Jashore, Bangladesh. We recruited 696 patients of both sex with UTI only infected by E coli. We had excluded the patients with UTI caused by other than E coli, female during menstruation, pregnancy, history of taking antibiotics within last 21 days, catheterization within 1 month and pelvic organ & genito urinary tract surgery within 6 months. Evaluation of antimicrobial resistance was done according to the standard bacteriological methods. Mean age of our study cases was 41.46±17.21 years with the range from 15 to 91 years. More than 85% participants were female with a sex ratio was 8:1.5. Reproductive age group ranged from 21 to 50 years was affected most commonly which constituted approximately two-third of our study. Our study revealed that the maximum antimicrobial resistance to E coli was Cotrimoxazole (95.0%), followed by Ceftazidime (75.7%), Gentamicin (70.3%), Amikacin (69.0%), Imipenam (58.9 %,), Cefixime (58.0%), Ciprofloxacin (57.3%), Azithromycin (56.0%), Cefuroxime (46.6%), Cefotaxime (37.4%), Ceftriaxone (35.2%), Meropenem (32.2%), Nitrofurantion (4.7%). With the high magnitude of antimicrobial resistance to E coli among the UTI patients even with extended generation of Cephalosporins, Carbapenams, Ciprofloxacin, Cotrimoxazole, Azithromycin and Aminoglycosides, our recommendation as first line empirical treatment option in UTI should be Nitrofurantoin due to low resistance pattern.},
 year = {2018}
}

Copy | Download

TY  - JOUR
T1  - Pattern of Antimicrobial Resistance to Escherichia Coli Among the Urinary Tract Infection Patients in Bangladesh
AU  - Goutam Kumar Acherjya
AU  - Keya Tarafder
AU  - Rina Ghose
AU  - Din Ul Islam
AU  - Mohammad Ali
AU  - Nazma Akhtar
AU  - Rajashish Chakrabortty
AU  - Satya Ranjan Sutradhar
Y1  - 2018/10/10
PY  - 2018
N1  - https://doi.org/10.11648/j.ajim.20180605.17
DO  - 10.11648/j.ajim.20180605.17
T2  - American Journal of Internal Medicine
JF  - American Journal of Internal Medicine
JO  - American Journal of Internal Medicine
SP  - 132
EP  - 137
PB  - Science Publishing Group
SN  - 2330-4324
UR  - https://doi.org/10.11648/j.ajim.20180605.17
AB  - Urinary Tract Infection (UTI) is very common in our day-to-day clinical practice. Among all the organisms Escherichia coli (E coli) is the most common but antimicrobial resistance becomes an alarming issue for UTI management now a days. Aim of this study is to assess the pattern of antimicrobial resistance to E coli among the UTI patients in Jashore, Bangladesh. This observational study was conducted from February, 2017 to January, 2018 in the district of Jashore, Bangladesh. We recruited 696 patients of both sex with UTI only infected by E coli. We had excluded the patients with UTI caused by other than E coli, female during menstruation, pregnancy, history of taking antibiotics within last 21 days, catheterization within 1 month and pelvic organ & genito urinary tract surgery within 6 months. Evaluation of antimicrobial resistance was done according to the standard bacteriological methods. Mean age of our study cases was 41.46±17.21 years with the range from 15 to 91 years. More than 85% participants were female with a sex ratio was 8:1.5. Reproductive age group ranged from 21 to 50 years was affected most commonly which constituted approximately two-third of our study. Our study revealed that the maximum antimicrobial resistance to E coli was Cotrimoxazole (95.0%), followed by Ceftazidime (75.7%), Gentamicin (70.3%), Amikacin (69.0%), Imipenam (58.9 %,), Cefixime (58.0%), Ciprofloxacin (57.3%), Azithromycin (56.0%), Cefuroxime (46.6%), Cefotaxime (37.4%), Ceftriaxone (35.2%), Meropenem (32.2%), Nitrofurantion (4.7%). With the high magnitude of antimicrobial resistance to E coli among the UTI patients even with extended generation of Cephalosporins, Carbapenams, Ciprofloxacin, Cotrimoxazole, Azithromycin and Aminoglycosides, our recommendation as first line empirical treatment option in UTI should be Nitrofurantoin due to low resistance pattern.
VL  - 6
IS  - 5
ER  -

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