Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst

Younes Abrouki; Abdelkader Anouzla; Hayat Loukili; Rabiaâ Lotfi; Ahmed Rayadh; My Abdellah Bahlaoui; Saı̈d Sebti; Driss Zakarya; Mohamed Zahouily

doi:doi:10.11648/j.ajac.20130102.12

Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst

Younes Abrouki, Abdelkader Anouzla, Hayat Loukili, Rabiaâ Lotfi, Ahmed Rayadh, My Abdellah Bahlaoui, Saı̈d Sebti, Driss Zakarya, Mohamed Zahouily

Published in American Journal of Applied Chemistry (Volume 1, Issue 2)

Received: 28 May 2013 Published: 30 June 2013

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Abstract

The aim of this study was to apply experimental design in the optimization of the thia-Michael addition reaction between chalcone derivatives and mercaptans catalyzed by Fluorapatite catalyst (FAP). The central composite design was used to design an experimental program to provide data to model the effects of various factors on reaction yield (Y). The variables chosen were catalyst weight (X1), reaction time (X2) and solvent volume (X3). The mathematical relationship of reaction yield on the three significant independent variables can be approximated by a nonlinear polynomial model. Predicted values were found to be in good agreement with experimental values. The optimum reaction conditions (x1= 350 mg, x2= 30 min and x3= 2 mL) for reaction model (chalcone and thiophenol) obtained by response surface were applied to other substrates. This study has shown that central composite design could efficiently be applied for the modeling of catalytic carbon-sulfur bond formation by FAP catalyst under mild reaction condition with high yield, and it is an economical way of obtaining the maximum amount of information with the fewest number of experiments.

Published in	American Journal of Applied Chemistry (Volume 1, Issue 2)
DOI	10.11648/j.ajac.20130102.12
Page(s)	22-27
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2013. Published by Science Publishing Group

Keywords

Carbon-Sulfur Bond Formation, Fluorapatite, Heterogenous Catalyst, Central Composite Design, Response Surface Methodology

References

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APA Style

Younes Abrouki, Abdelkader Anouzla, Hayat Loukili, Rabiaâ Lotfi, Ahmed Rayadh, et al. (2013). Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst. American Journal of Applied Chemistry, 1(2), 22-27. https://doi.org/10.11648/j.ajac.20130102.12

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ACS Style

Younes Abrouki; Abdelkader Anouzla; Hayat Loukili; Rabiaâ Lotfi; Ahmed Rayadh, et al. Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst. Am. J. Appl. Chem. 2013, 1(2), 22-27. doi: 10.11648/j.ajac.20130102.12

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AMA Style

Younes Abrouki, Abdelkader Anouzla, Hayat Loukili, Rabiaâ Lotfi, Ahmed Rayadh, et al. Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst. Am J Appl Chem. 2013;1(2):22-27. doi: 10.11648/j.ajac.20130102.12

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@article{10.11648/j.ajac.20130102.12,
  author = {Younes Abrouki and Abdelkader Anouzla and Hayat Loukili and Rabiaâ Lotfi and Ahmed Rayadh and My Abdellah Bahlaoui and Saı̈d Sebti and Driss Zakarya and Mohamed Zahouily},
  title = {Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst},
  journal = {American Journal of Applied Chemistry},
  volume = {1},
  number = {2},
  pages = {22-27},
  doi = {10.11648/j.ajac.20130102.12},
  url = {https://doi.org/10.11648/j.ajac.20130102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20130102.12},
  abstract = {The aim of this study was to apply experimental design in the optimization of the thia-Michael addition reaction between chalcone derivatives and mercaptans catalyzed by Fluorapatite catalyst (FAP). The central composite design was used to design an experimental program to provide data to model the effects of various factors on reaction yield (Y). The variables chosen were catalyst weight (X1), reaction time (X2) and solvent volume (X3). The mathematical relationship of reaction yield on the three significant independent variables can be approximated by a nonlinear polynomial model. Predicted values were found to be in good agreement with experimental values. The optimum reaction conditions (x1= 350 mg, x2= 30 min and x3= 2 mL) for reaction model (chalcone and thiophenol) obtained by response surface were applied to other substrates. This study has shown that central composite design could efficiently be applied for the modeling of catalytic carbon-sulfur bond formation by FAP catalyst under mild reaction condition with high yield, and it is an economical way of obtaining the maximum amount of information with the fewest number of experiments.},
 year = {2013}
}

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TY  - JOUR
T1  - Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst
AU  - Younes Abrouki
AU  - Abdelkader Anouzla
AU  - Hayat Loukili
AU  - Rabiaâ Lotfi
AU  - Ahmed Rayadh
AU  - My Abdellah Bahlaoui
AU  - Saı̈d Sebti
AU  - Driss Zakarya
AU  - Mohamed Zahouily
Y1  - 2013/06/30
PY  - 2013
N1  - https://doi.org/10.11648/j.ajac.20130102.12
DO  - 10.11648/j.ajac.20130102.12
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 22
EP  - 27
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20130102.12
AB  - The aim of this study was to apply experimental design in the optimization of the thia-Michael addition reaction between chalcone derivatives and mercaptans catalyzed by Fluorapatite catalyst (FAP). The central composite design was used to design an experimental program to provide data to model the effects of various factors on reaction yield (Y). The variables chosen were catalyst weight (X1), reaction time (X2) and solvent volume (X3). The mathematical relationship of reaction yield on the three significant independent variables can be approximated by a nonlinear polynomial model. Predicted values were found to be in good agreement with experimental values. The optimum reaction conditions (x1= 350 mg, x2= 30 min and x3= 2 mL) for reaction model (chalcone and thiophenol) obtained by response surface were applied to other substrates. This study has shown that central composite design could efficiently be applied for the modeling of catalytic carbon-sulfur bond formation by FAP catalyst under mild reaction condition with high yield, and it is an economical way of obtaining the maximum amount of information with the fewest number of experiments.
VL  - 1
IS  - 2
ER  -

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Author Information

Younes Abrouki

Department of Research, Faculty of Science and Technology, University Hassan II, Mohammedia, Morocco
Abdelkader Anouzla

Department of Research, Faculty of Science and Technology, University Hassan II, Mohammedia, Morocco
Hayat Loukili

Department of Research, Faculty of Science and Technology, University Hassan II, Mohammedia, Morocco
Rabiaâ Lotfi
Ahmed Rayadh

Department of Research, Faculty of Science and Technology, University Hassan II, Mohammedia, Morocco
My Abdellah Bahlaoui

Department of Research, Faculty of Science and Technology, University Hassan II, Mohammedia, Morocco
Saı̈d Sebti
Driss Zakarya

Department of Research, Faculty of Science and Technology, University Hassan II, Mohammedia, Morocco
Mohamed Zahouily

Department of Research, Faculty of Science and Technology, University Hassan II, Mohammedia, Morocco

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APA Style

Younes Abrouki, Abdelkader Anouzla, Hayat Loukili, Rabiaâ Lotfi, Ahmed Rayadh, et al. (2013). Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst. American Journal of Applied Chemistry, 1(2), 22-27. https://doi.org/10.11648/j.ajac.20130102.12

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ACS Style

Younes Abrouki; Abdelkader Anouzla; Hayat Loukili; Rabiaâ Lotfi; Ahmed Rayadh, et al. Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst. Am. J. Appl. Chem. 2013, 1(2), 22-27. doi: 10.11648/j.ajac.20130102.12

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AMA Style

Younes Abrouki, Abdelkader Anouzla, Hayat Loukili, Rabiaâ Lotfi, Ahmed Rayadh, et al. Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst. Am J Appl Chem. 2013;1(2):22-27. doi: 10.11648/j.ajac.20130102.12

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@article{10.11648/j.ajac.20130102.12,
  author = {Younes Abrouki and Abdelkader Anouzla and Hayat Loukili and Rabiaâ Lotfi and Ahmed Rayadh and My Abdellah Bahlaoui and Saı̈d Sebti and Driss Zakarya and Mohamed Zahouily},
  title = {Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst},
  journal = {American Journal of Applied Chemistry},
  volume = {1},
  number = {2},
  pages = {22-27},
  doi = {10.11648/j.ajac.20130102.12},
  url = {https://doi.org/10.11648/j.ajac.20130102.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajac.20130102.12},
  abstract = {The aim of this study was to apply experimental design in the optimization of the thia-Michael addition reaction between chalcone derivatives and mercaptans catalyzed by Fluorapatite catalyst (FAP). The central composite design was used to design an experimental program to provide data to model the effects of various factors on reaction yield (Y). The variables chosen were catalyst weight (X1), reaction time (X2) and solvent volume (X3). The mathematical relationship of reaction yield on the three significant independent variables can be approximated by a nonlinear polynomial model. Predicted values were found to be in good agreement with experimental values. The optimum reaction conditions (x1= 350 mg, x2= 30 min and x3= 2 mL) for reaction model (chalcone and thiophenol) obtained by response surface were applied to other substrates. This study has shown that central composite design could efficiently be applied for the modeling of catalytic carbon-sulfur bond formation by FAP catalyst under mild reaction condition with high yield, and it is an economical way of obtaining the maximum amount of information with the fewest number of experiments.},
 year = {2013}
}

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TY  - JOUR
T1  - Central Composite Experimental Design Applied to the Catalytic Carbon-Sulfur Bond Formation by Fluorapatite Catalyst
AU  - Younes Abrouki
AU  - Abdelkader Anouzla
AU  - Hayat Loukili
AU  - Rabiaâ Lotfi
AU  - Ahmed Rayadh
AU  - My Abdellah Bahlaoui
AU  - Saı̈d Sebti
AU  - Driss Zakarya
AU  - Mohamed Zahouily
Y1  - 2013/06/30
PY  - 2013
N1  - https://doi.org/10.11648/j.ajac.20130102.12
DO  - 10.11648/j.ajac.20130102.12
T2  - American Journal of Applied Chemistry
JF  - American Journal of Applied Chemistry
JO  - American Journal of Applied Chemistry
SP  - 22
EP  - 27
PB  - Science Publishing Group
SN  - 2330-8745
UR  - https://doi.org/10.11648/j.ajac.20130102.12
AB  - The aim of this study was to apply experimental design in the optimization of the thia-Michael addition reaction between chalcone derivatives and mercaptans catalyzed by Fluorapatite catalyst (FAP). The central composite design was used to design an experimental program to provide data to model the effects of various factors on reaction yield (Y). The variables chosen were catalyst weight (X1), reaction time (X2) and solvent volume (X3). The mathematical relationship of reaction yield on the three significant independent variables can be approximated by a nonlinear polynomial model. Predicted values were found to be in good agreement with experimental values. The optimum reaction conditions (x1= 350 mg, x2= 30 min and x3= 2 mL) for reaction model (chalcone and thiophenol) obtained by response surface were applied to other substrates. This study has shown that central composite design could efficiently be applied for the modeling of catalytic carbon-sulfur bond formation by FAP catalyst under mild reaction condition with high yield, and it is an economical way of obtaining the maximum amount of information with the fewest number of experiments.
VL  - 1
IS  - 2
ER  -

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